Nootropic Powder Semax ACTH (4-7) for Brain Immune
Semax powder
is what's called a synthetic heptapeptide, meaning that it's a chain of
7 amino acids as a single molecule. Interestingly enough, the semax
molecule mirrors a fragment of adrenocorticotropic hormone, which is
released in the pituitary gland of humans in response to environmental
stress.
It was originally developed in Moscow, Russia as a
treatment mostly for neurological-related disorders, such as poor
memory, depression, ADHD, and post-stroke treatment.
Additionally, Semax can be used as an immune-system booster or as a treatment for peptic ulcers, strangely enough.
Semax can also be used off-label as a nootropic, with many properties that make it quite suitable for regular use.
Benefits of Semax:
In
between the 2 - 3 decades since semax was synthesized and tested, there
have been numerous studies on animals and humans to see the benefits of
the drug. One of the primary benefits of semax is as a cognitive
enhancer. One 2 day study of power plant workers tested semax and memory
formation. The 1 mg dose 1 hour prior to the exam showed a drastic
increase in correct responses.
The mechanism for improving
cognitive function relates to brain chemicals like BDNF and NGF. Semax
can increase BDNF and NGF by 8 and 5 times the baseline. Numerous other
studies have confirmed the increase in BDNF, which acts as a type of
fertilizer for the brain to develop new neurological connections.
Another
way semax improves cognitive abilities is through the increase of alpha
brain wave states. EEG studies show semax can increase alpha brain
waves in patients, but also can prevent negative EEG changes during
stressful situations (hyperventilation).
The benefits for alpha
brain waves may also help support positive mood enhancement and
reducing anxiety. Semax benefits include reducing symptoms of stress and
depression. The Journal of Psychophysiology published a study on the
sedative effects of semax on those who were suffering from mental
illness. Part of these benefits may come from an increase in serotonin
turnover, which is traditionally done with SSRIs.
Finally, an
interesting but not incredibly well-researched benefit of semax is as
for stimulant potentiation. Studies show that semax in combination with
stimulants (such as amphetamine) could increase the dopamine release
from the drug. One study showed an increase of activity from 182% (just
the amphetamine) versus 261% (amphetamine and semax).
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