Citicoline Sodium, also known as cytidine diphosphate-choline
(CDP-Choline) & cytidine 5'-diphosphocholine is a
psychostimulant/nootropic. It is an intermediate in the generation of
phosphatidylcholine from choline. Studies suggest that CDP-choline
supplements increase dopamine receptor densities, and suggest that CDP
choline supplementation helps prevent memory impairment resulting from
poor environmental conditions.
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Preliminary research has found that citicoline supplements help
improve focus and mental energy and may possibly be useful in the
treatment of attention deficit disorder.Citicoline has also been shown
to elevate ACTH independently from CRH levels and to amplify the release
of other HPA axis hormones such as LH, FSH, GH and TSH in response to
hypothalamic releasing factors.These effects on HPA hormone levels may
be beneficial for some individuals but may have undesirable effects in
those with medical conditions featuring ACTH or cortisol hypersecretion
including, but not limited to, PCOS, type II diabetes and major
depressive disorder.
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