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Pindolol powder
Indapamide is a thiazide-like diuretic drug marketed by Servier,
generally used in the treatment of hypertension, as well as
decompensated heart failure. Combination preparations with perindopril
(an ACE inhibitor antihypertensive) are also available.
Indapamide is currently the most popular non-prescription diuretic
antihypertensive drug with good efficacy, stable blood pressure, fewer
side effects, etc.
Indapamide Application
Indapamide is used to treat high blood pressure. Indapamide is also used
to reduce extra salt and fluid in the body (edema) caused by a certain
heart problem (congestive heart failure). Lowering high blood pressure
helps prevent strokes, heart attacks, and kidney problems. Decreasing
extra salt and fluid in the body helps to decrease swelling and
breathing problems from congestive heart failure and increases your
ability to exercise.
Indapamide have diuretic and calcium antagonist dual effect by
inhibiting the proximal end of the distal convoluted tubule Na+
reabsorption, resulting in diuresis, while by blocking Ca2+ influx
especially a higher selectivity for vascular smooth muscle to dilate the
small blood vessels of the outer periphery, resulting in
antihypertensive effect. But the effect to vascular smooth muscle is
stronger than the diuretic effect.
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