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Brands Shy Away From Celebrity Marketing in China
What Happened: China’s “traffic stars” may be fading out of favor. According to a recent report by Shiqu Insight Engine, celebrity marketing events in March 2022 fell by 50.9 percent compared with the same period last year. Conversely, co-branded marketing and new product marketing surged 91.3 percent and 57.6 percent, respectively, while sports marketing jumped 6.6 times.To get more chinese entertainment news, you can visit shine news official website.
The Jing Take: “Traffic stars,” a Chinese term for KOLs who drive high digital traffic, have helped brands achieve explosive growth for their new products. Although a decline of celebrity events could be partially attributed to the ongoing pandemic — with Shanghai still in lockdown and Shenzhen just recovering — it points more so to the shifting tides in China’s entertainment industry. From Kris Wu’s sexual assault scandal last year to the more recent tax evasion cases of livestreamer Viya and actor Deng Lun, brands that don’t respond quickly enough to their ambassadors’ bad behavior are finding themselves caught in the crossfire, too.
Fortunately, there are other options. As the Winter Olympics proved, sports stars can be just as effective at marketing. Take Anta and Tiffany & Co., who signed with freestyle skier Eileen Gu early and scored big when she won gold in February; sales of the red Anta ski suit Gu wore during the competition surged 20-fold while her Tiffany rings and bangles trended on Chinese social media. Similarly, Prada racked up over 46 million views on Douyin for its Spring/Summer 2022 collection after creating a video campaign centered around four Chinese Olympic athletes.
Co-branded drops are also a safer alternative, although brands are not exempt from netizen backlash if they commit a faux pas. Ultimately, globally players that want to fuel long-term growth in China rather than one-off sales should look beyond traffic stars — and focus on building their reach instead of just borrowing it. As the saying goes, the brightest stars burn the quickest. And brands don’t want to be around when things go up in flames.
The Jing Take reports on a piece of the leading news and presents our editorial team’s analysis of the key implications for the luxury industry. In the recurring column, we analyze everything from product drops and mergers to heated debate sprouting on Chinese social media.
The Art of China’s Empresses Reveals Their Powerful
At the onset of Empresses in the Palace, the 2011 miniseries that caused a sensation in China, a beautiful young woman, Zhen Huan, is paraded before the emperor. She is one of many marriage-age girls who have been summoned to Beijing’s Forbidden City to be considered for the Yongzheng Emperor’s harem. Although it is an honor to be chosen as an imperial consort, Zhen is dismayed—she must leave her family behind and enter into a new life of luxury, restriction, and scheming ambition.To get more news about last empress of china, you can visit shine news official website.
In the historical epic, set against the backdrop of the flourishing Qing Dynasty (1644–1912) in the 18th century, Zhen navigates the treacherous, strictly regulated court, where eight ranks of consorts compete with the top empress and vye for the emperor’s attention. (While there was only one empress at a time, the larger lower ranks could move up the social ladder, especially by bearing sons.) At the top of this food chain stood the empress dowager—a consort who had either installed her son on the throne, or was the widowed primary wife of a previous emperor.
The real women who lived in the palace are shrouded in mystery, but Daisy Yiyou Wang and Jan Stuart—the curators of a new exhibition that delves into the empresses’ lives—emphasize that the TV show is a dramatization. At least, there’s not enough evidence to prove that the salacious backstabbing and love affairs that dominate the plot actually took place.
“Empresses of China’s Forbidden City, 1644–1912,” a collaboration between the Palace Museum in Beijing; the Peabody Essex Museum in Salem, Massachusetts; and the Freer and Sackler Galleries in Washington, D.C. (where it is now on view), capitalizes on the popularity of such costume dramas. The exhibition centers on five empresses’ little-acknowledged influence on art, religion, and politics through the furniture and objects they used, the paintings they enjoyed, and the jewelry and clothes they wore.
The relative obscurity of these women runs counter to our understanding of royalty today. “If you watch the royal wedding in England, it’s a public affair, a spectacle,” Wang said. “Back then, imperial women were probably completely invisible to the general public.” In European monarchies, copies of rulers’ portraits were circulated around the world for others to venerate; in China, access to imperial powers was a privilege, their images considered sacred.
The curators also knew they were up against pernicious gender bias in their field. Scholars of Chinese art history generally believed that women at court had access to inferior art, fashion, and decorations compared to those used by the emperor. “People questioned us from the beginning because we didn’t think objects used by women and made for women were secondary art objects,” Wang said. She was convinced that some of the most spectacular pieces in the Palace Museum collection were enjoyed by powerful women. She was right.
The curators found that the quality of art and objects owned by these high-ranking ladies matched those of the emperor, though they didn’t always feature the same motifs. “There’s a longstanding thought in Chinese culture that if you have good omens, images of what is desired surrounding a person, that can help actualize the goal,” Stuart said. Thus, women in the court found themselves surrounded by images of mothers and sons, or symbols suggesting fertility—a woman holding a seeded gourd, or two interlocking jade circles, a reference to continuity.
Their quarters were decorated with exquisite pieces of furniture. One delicate lacquer cabinet in the exhibition—whose staggered shelves offer discreet places to put personal treasures—is painted with a delicate landscape scene and auspicious motifs like the bat. Each piece in an empress’s living space was similarly spectacular and refined.
Still, the lives and activities of these women have been obscured for centuries. The Qing court, like many other monarchies around the world, had a patrilineal structure. There was a tradition to record the emperor’s life in great detail, but no such tradition for his wives. “To say they’re not documented at all,” however, “would be a false statement,” Wang said.
Often, the influence of the empresses is only obliquely referenced in archival documents written by the emperor, and so they are characterized from their husband’s or son’s point of view. “Although it’s not strictly articulated, you can get a very strong hint that many of these women were educated, they could talk about state affairs, and be the soulmate of their husband,” Wang said. The empress was also expected, like women all over China, to be a good household manager.
How To Safely Use Public Wi-Fi Networks
Wi-Fi hotspots in coffee shops, libraries, airports, hotels, universities, and other public places are convenient, but often they’re not secure. If you connect to a Wi-Fi network and send information through websites or mobile apps, someone else might be able to see it. Here are some ways to safely use public Wi-Fi when you’re out and about.To get more news about smart home security products, you can visit securamsys.com official website.
When you’re at home, you can take steps to keep your home wireless network secure — like using a strong router password, limiting what devices can get onto your network, and turning on encryption, which scrambles the information you send over the internet into a code that can’t be read by others. But when you’re using your favorite coffee shop’s Wi-Fi, there’s not a lot you can do to control its network security.
Why does it matter? If the network isn’t secure, and you log into an unencrypted site — or a site that uses encryption only on the sign-in page — other users on the network can see what you see and send. They could hijack your session and log in as you. New hacking tools — available for free online — make this easy, even for users with limited technical know-how. Your personal information, private documents, contacts, family photos, and even your login credentials could be up for grabs.
A scammer also could use your account to impersonate you and scam people onyour contact lists, or test your usernames and passwords on other websites — including sites that store your financial information. If a scammer gets your personal or financial information, they could steal your identity.
When you sign on to public Wi-Fi, you may also be sharing your data with the companies providing the Wi-Fi. Many public Wi-Fi networks such as in airports and hotels will also prompt you to install a “digital certificate” to use their internet. They may do this to scan your traffic for malware — but this also allows them to read your traffic, even if it’s to a site using https (which encrypts information).
While there isn’t much you can do to make a public Wi-Fi network more secure, you can do some things to help keep your data secure on public Wi-Fi:
Connect to websites securely. If you see https in the web address, you have a secure connection to the website. But using https does not mean a website is legit. Scammers know how to encrypt sites, too. They know that people assume https means a website is safe — so they’ve started adding it to their websites, as well. So your data is encrypted on its way to the site, but it won’t be safe from scammers operating that site.
Consider using a VPN app. Some virtual private networks, known as VPNs, offer encryption. Learn more about VPN apps and what to know before you download one.
Use your mobile data. Your mobile data is usually encrypted. If you’re on the go, don’t have the option of using a secure website, and have no VPN encryption, consider using your mobile data instead of Wi-Fi. This is a good option when you’re putting personal information into apps, since it can be hard to know if they’re encrypted.
Don’t access your personal or financial information. Always assume a public Wi-Fi network isn’t secure.
Log in or send personal information only to websites you know are fully encrypted. To be secure, your entire visit to each site should be encrypted (meaning that the URL starts with https) — from the time you log in to the site until you log out. If you think you’re logged in to an encrypted site but find yourself on an unencrypted page, log out right away.
Don’t stay permanently signed in to accounts. When you’ve finished using an account, log out.
Don’t use the same password on different websites. It could give someone who gains access to one of your accounts access to many of your accounts.
Pay attention to warnings. Many web browsers alert you before you visit a scammy website or download malicious programs. Don’t ignore those warnings. Also keep your browser and security software up to date.
BUILT FOR THE LONG HAUL
The Goodyear Tire & Rubber Company (NASDAQ: GT) today announced a new addition to its lineup of hardworking Wrangler® tires, the Goodyear Wrangler Workhorse® HT. Engineered to deliver dependable all-season traction, the Wrangler Workhorse HT provides a smooth, confident ride and the strength to go the extra mile.To get more news about long haul tires, you can visit gofortunetire.com official website.
Backed with a 60,000-mile treadwear limited warranty*, the Wrangler Workhorse HT features a long-wearing tread compound designed to deliver dependable tread life and traction in wet, dry and light snow driving conditions.The Wrangler Workhorse HT delivers drivers exactly what its name implies: durable, long-lasting performance and the toughness to excel wherever your day or job takes you," said Michiel Kramer, director of Consumer Product Marketing at Goodyear. "We engineered the Wrangler Workhorse HT to be dependable and versatile in rain, sleet or shine."
The Goodyear Wrangler Workhorse HT is available in 34 sizes and is compatible with a wide range of today's most popular sport utility vehicles (SUVs) and pick-up trucks. Select LT and C-type sizes incorporate innovative soybean oil technology within the tread compound, which replaces a portion of the petroleum-based materials used in production. This is another important step in Goodyear's global journey to fully replace petroleum-derived oils in its tires by 2040.
Goodyear Wrangler Workhorse HT tires are a good choice for a number of all-terrain vehicles, including the Ford Explorer, Escape and F-Series; the Chevrolet Silverado, Traverse and Tahoe; the Toyota Tundra, Tacoma and 4Runner; the GMC Acadia, Yukon and Sierra; and the Honda CR-V, Odyssey and Pilot.
Why Ebike Need Suspension?
Whether you are newbies or bike experts, a common question for them is do they need suspension on their bikes? Of course, it is a useful component, but it is not a must-have part based on your own needs.To get more news about full suspension electric mountain bike, you can visit magicyclebike.com official website.
With electric bikes, this question is even more common. While ebike experts may know deeply about ebike suspension, those rookies could be pretty confused about it. So today, we will tell you things that you want to be aware of about ebike suspension. Also, you will find out if you need a suspension on your electric bikes.
Why Do You Need Suspension on An Electric Bike?
Electric bikes for adults can enable you to travel on all kinds of terrains, but maybe you’ve heard that not all terrains are completely equal before. When it comes to flat and smooth city streets and roads, you are able to gain a wonderful riding experience. However, if you are riding on dirt, sand, gravel, hills, and other bumpy and rugged terrains, the rides won’t be as smooth because of the shocks and vibration resulting from bumps and rocks.
Occasionally, it might not be difficult to tolerate those bumps on an ebike without suspension, but if that remains for a long time, well, trust me, it will be really annoying and uncomfortable.
And things can be worse than that. With shocks and shaking, you may fall off your ebike and get hurt more easily. That is why manufacturers create suspension systems. It is to make your ebike rides much safer and more comfortable.
More Comfort: As I said above, with an electric bike suspension, your electric bike rides can be much more comfortable. That is because the suspension system plays a major role in absorbing shocks from bumps and decreasing the strain you feel while riding on rugged terrains. Therefore, it is really essential to have a suspension, especially for those who want to take adventures on mountain bike trails. For instance, some people tend to use an electric mountain bike when it comes to riding off-road. The reason is that an electric mountain bike is usually specialized to have a professional suspension system.
Smooth Control: An suspension is able to provide more traction for an electric mountain bike. Traction is something that helps tires have more contact on the ground. Therefore, it will be easier to control your ebikes.
Besides electric bike suspension, a pair of hydraulic disc brakes can help you gain smooth control as well. They are able to provide you with strong braking power. When it comes to applying them, you could pull the brake levers with only 1 or 2 fingers.
Longer Lifespan: In fact, an electric bike suspension does need a lot of maintenance, but it can maximize the lifespan of an ebike frame. By absorbing shocks and shaking from bumps on the roads, your ebike frame will not wear down so quickly. And again, this is also true for electric mountain bikes.
Cons
More Price: The price could be a little problem. Normally, an ebike with a suspension will be a lot more expensive, but it is not difficult to understand. You can take it as adding an extra piece of gear. Even something like a suspension post can cost you $100 - $150, but to get a better experience, it is worth the price.
Heavier: Compared with traditional bikes, electric bikes for sale are way heavier with motors, batteries, ebike fat tires, and some other electric components. And the frame also serves as a major part of the total weight of an ebike. An electric bike suspension can increase the overall weight.
Much Maintenance: There is a lot of work to do about maintaining electric bike suspension, like oiling and replacements. This kind of maintenance requires professional skills, and most of the time, you will have to get to a bike shop. If you don’t maintain the ebike suspension appropriately, your electric bike performance will be more or less degraded.
Full-suspension electric bikes mean that they got a suspension fork up front and another suspension for the rear wheel. Both front and rear have suspension. Their advantage is basically the comfort and the handling. There's really nothing that compares to a full-suspension bike when it comes to comfort. Anything you hit whether It's with the front wheel or the rear wheel, you're going to have that nice dampening, which will make you ride so much nicer if you're going to be doing lots of commuting and street riding.
Whether or not you need that, it is sort of a personal question if you're doing a lot of off-road, and definitely, a full-suspension electric bike is almost a must on some more technical terrain. You can certainly do off-road riding with just a hardtail ebike, but the more technical terrain you are riding on, the better handling you want. The downside here is usually going to be the increased price and the weight.
TOP ELECTRIC BIKE SERVICE AND MAINTENANCE TIPS
If you’re already enjoying the wonders of assisted pedalling, or are thinking of investing in an electric bike, then you’ve probably started to think about the implications of having a battery, motor and other components to look after alongside the bike itself. How can I save money on an e-bike? How long will an electric bike battery last? How long does an electric bike motor last? How much is it going to cost me to replace these, and when will I need to do it?To get more news about ebike maintaince, you can visit magicyclebike.com official website.
The truth is, with a bit of TLC and PPM (planned, preventative maintenance), you can make your e-bike’s battery and motor last much longer than the manufacturer’s recommendation. Just like a normal bike, knowing what to look out for and carrying out a few basic fixes can help you to avoid serious bills further down the line.
Plus, with the cost of living crisis continuing, we’re all trying to make our money go further and avoid replacing things before we need to. So, here are our top electric bike maintenance tips to make sure your electric bike and its components will keep on going for as long as possible.
Keep it clean
One of the simplest bike maintenance tips in the book, scrubbing your after each ride will stop muck and dirt from interfering with not just any electronics, but also the bike itself. Most electric bikes are water resistant, so you can go ahead and clean them like you would a normal bike, but we’d advise removing the battery before you start, and only using cleaning products that are recommended for use with bikes.
Take care not to use a pressure washer, as this can cause water to enter sensitive areas or strip grease away from places it’s needed, like around your wheel bearings and bottom bracket. The garden hose is fine for a quick rinse, then give it a good scrub with a sponge or cloth and your preferred bike cleaning products. Dry everything off with a towel and leave your e-bike for a little while before reconnecting the battery to make sure no residual water comes into contact with battery contact points or other sensitive areas.
The secret to making electric bikes last longer is all down to reducing the amount of resistance at key points on your bike. Friction between the moving parts on your bike and damage from dirt and rust are some of the main causes for components wearing out, so make sure your chain, wheels and brakes have sufficient lubrication to avoid surfaces from coming into contact too often.
Use a wet lube if you’re going to be cycling in wet conditions or a dry lube if you’re cycling in summer on your chainset and re-apply any grease to your bearings and bottom bracket regularly, especially in the wet or if you wash your bike regularly.
Depending on the weather, Muc-Off Dry or Wet Lube will go a long way to making your chain and chainset last much longer, but a bit of additional lube or some M094 spray on other moving parts won’t hurt.
Bike grease is your other secret weapon when it comes to prolonging your e-bike’s life – make sure your bearings and bottom bracket are suitably greased to reduce wear and tear. Just take care not to get lubes or sprays anywhere near battery contact points or other sensitive areas on your e-bike.
Teach yourself basic bike maintenance
Even though your electric bike is packed with loads of technical kit, the bike itself probably going to be the same as any other in terms of materials and components. From repairing punctures to learning how to replace brake cables, knowing how to do some of the more fiddly jobs will not only allow you to get your electric bike back on the road, but also spot some problems before they happen.
Our Cycling Help and Advice Centre is a great starting point for novice bike mechanics who want to be able to keep their e-bike in good condition. With plenty of videos and step-by-step advice, you can pick up the basics of bike servicing and start to lengthen your e-bike’s lifespan.
How to Pick The Best E-bike Accessories
It's always essential to have a set of accessories to avoid unpleasant situations on the road. The right tools can enhance your safety, facilitate tasks, and improve your overall riding experience, regardless of the vehicle you're using. E-bike accessories are no exception.To get more news about ebike accessories, you can visit magicyclebike.com official website.
Buying accessories for your E-bike helps avoid headaches in the long run and makes it feel truly yours with added customization and optimization to fit your needs. So keep reading for some ideas on valuable upgrades to improve your riding experience.
Safety on the Road
The first thing you should worry about after purchasing your E-bike is how to make it safer. The most basic accessory for any bike, be it a regular one, an E-bike, or a motorcycle, is a helmet.
While there are many helmet options, the most important thing about them is that they fit you well. So adjustable helmets are a great pick if you're unsure. Some helmets also have LED safety lights for additional safety while riding at night.
Dealing with Flat Tires
Flat tires are inevitable and unpredictable. A repair kit is the best option since carrying a spare tire is difficult.
You should consider carrying tire patches, a multitool, a tire lever, and a tire pump with you. When choosing an inner tube repair kit, make sure the patches come in different sizes and can be easily applied.
Essential Maintenance
Doing maintenance yourself cuts down the cost of maintaining your E-bike significantly. Any E-bike owner can benefit from having a bike kit to help disassemble their bike to oil, fix, or clean it.
The best kits include wrenches, hex keys, spare chain links, chain tools, and patches. Essentially, anything that can assist in taking apart your E-bike without effort.
Be sure that your wrenches and hex keys are made of steel to avoid oxidation and ensure longevity.
Spare Batteries for Long Routes
Spare batteries are essential for long trails or crossing the town. Knowing the difference between batteries is vital to picking the best option for your needs.
Lithium Cobalt batteries (LCo) have a higher density that lasts longer.
Lithium Manganese (LiMg204) is the latest in battery technology. It's eco-friendly, keeps its performance at higher temperatures, and doesn't cost quite as much.
If you constantly travel and would like to take your E-bike along for the ride, check out how to deal with the batteries on a plane to avoid issues.
Riding in The Rain
Preparing for bad weather is crucial if you work with your bike or use it to commute. Good fenders can ensure you get to your destination dry and clean.
However, avoid fenders made of iron or plastic. They quickly get eroded by the elements and end up damaging your bike's frame.
Good fenders should be made of aluminum, PVC, stainless steel, or a combination of those materials to ensure greater durability while avoiding damage to your clothing.
The Best Rat Traps for Your Money in 2022
Rats can be more than just an occasional nuisance, often doing thousands of dollars of damage in a short time.To get more news about Rat Board, you can visit senpinghz.com official website.
We home-tested 10 popular models employing different means of trapping and disposing of rats and other vermin, concentrating on effectiveness, ease of use, capacity, and occupant disposition.
Our top choice is the Rat Zapper RZC001-4 Classic Rat Trap, which proved the most effective and user-friendly. Here are our choices for the best rat traps.This trap is as antiseptic as it gets, with no tactile or even visual contact needed. Its best feature is the LED light that flashes red when a rat is inside, letting you know it's time to empty the trap without having to look. (Cleaning is necessary between uses, however.)
The purple, tunnel-shaped trap is completely opaque, so you never need to see the results of its use, which it accomplishes through high-voltage shock. You know the job is done when its best feature, a little LED light, flashes red; then, you can empty it without having to look. The four AA batteries (not included) supply enough power to last for 20 encounters, according to the manufacturer, which is great if you have mice issues as well. It also is big enough for larger rodents but is not intended for outdoor use.
Victor has been making the classic wood-and-metal snap trap for over 100 years! Inexpensive and straightforward, this is the classic choice for those looking to save money and who are familiar with using the design: You set the bait, set the trap, and wait for the result.
However, the trap can be difficult to set and is easy to trigger, meaning you can accidentally end up pinching your fingers. Also, this trap may not be immediately effective, causing the animal to suffer.1 And, of course, disposal requires direct contact. But if budget is your prime consideration, we recommend this one.
If you want to avoid inhumane traps or poison, this is our best pick for a nontoxic bait. The manufacturer, EcoClear, says the product avoids unintentional harm to children, pets, and the environment. The bait is specific to rats' unique digestive system and doesn't harm non-targeted animals or pests.
Given its nontoxic makeup,2 it is safe to use indoors and outdoors. Our testers liked the ability to use it in stables and barns, as the threat to other animals is low. However, this bait is slow-acting compared with the other trapping methods.
Many people seek out glue traps because of their inexpensive price points and because they do not use rodenticides: They just trap the interloper for humane disposal. This is why glue-based traps remain a standard in pest control: They perform exactly as advertised.
Customers liked this model because anchors kept the trap where it was positioned. Each pack in this product contains six traps that are effective for up to one year, offering the ability to use them as long-term monitoring tools to keep tabs on your population.Tomcat is one of the oldest manufacturers in the rodent control market. Their Indoor/Outdoor Rat Snap Traps are ideal when you likely have many rats to contend with and need to set traps indoors and out. Using plastic instead of classic metal allows for more design choice. In this case, that resembles clamping alligator jaws, which are intended to keep rats in place with less chance of escape.
Customers liked the updated setting-up-bait process, which avoided putting delicate fingers in harm's way. (You can arm it with your foot if you choose.) Plastic, which doesn't rust, also extends the shelf life. However, just as in the metal-and-wood variation, sometimes the jaws don't deliver a lethal blow, and the results aren't concealed.
What Is Butyl Tape and How Do You Use It?
If you own an RV you need to know what butyl tape is, because its used in many places for sealing out water. Its not only for RV’s however as its used in many construction applications where a water-tight seal is needed. This includes roofing, plumbing, aviation, and marine construction applications.To get more news about Butyl Tape, you can visit senpinghz.com official website.
When you’re on the road a lot with your RV, it’s important to have the right tools and materials for simple fixes along the ride. RV butyl tape is one of those essential materials. Little things can go wrong sometimes, but proper preparation makes those issues much less intrusive to the schedule.
You are likely aware of the usability and versatility of duct tape, but do you understand the excellence of butyl tape? If not, you need to read on. Learn more about what it is and what it does, and you’ll be a better adventurer for it.
What Is Butyl Tape?
Silicone, rubber, and acrylic are the three main types of adhesives. Butyl tape is a pressure-sensitive rubber-based adhesive, synthetic rubber at that. It’s a solvent-based adhesive crafted in a laboratory environment rather than the natural environment of a rubber tree.
Since rubber is sensitive to temperature changes, butyl tape’s formula makes it a little more tolerant of temperature shifts. It stays more flexible when the temperatures are cold and doesn’t get as flimsy in extremely warm temperatures. This makes it an excellent sealant/bonding agent for many practical applications.
Butyl tape is not intended to hold things together on its own but acts more as a seal between a joint. Wall and roof fixtures should have butyl applied between them and the surface they are mounted to act as another barrier to moisture. The tape is best when squished by means of a screw. In fact, a great way to use it is behind locations where screws penetrate. This will add another layer of water protection around the screw.
How Long Will Butyl Tape Last?
If you’re talking shelf life, we have found printed shelf life of five years. However, that doesn’t mean the tape will just be useless the day after the five-year mark. It’s just how long the manufacturer can guarantee you will get good use out of it.
As for applications, we have helped remodel a 40-year-old RV that had lots of original butyl tape in it that was still flexible and doing its job well. There is not much that degrades it besides solvents, so as long as it doesn’t get soaked in gasoline, turpentine, or other solvents it will stay usable for a very, very long time.
CaCO3–Chitosan Composites Granules for Instant Hemostasis and Wound Healing
Excessive bleeding induces a high risk of death and is a leading cause of deaths that result from traffic accidents and military conflict. In this paper, we developed a novel porous chitosan–CaCO3 (CS–CaCO3) composite material and investigated its hemostatic properties and wound healing performance. The CS–CaCO3 composites material was prepared via a wet-granulation method. Granulation increases the infiltrating ability of the CS–CaCO3 composites material. The improved water absorption ability was enhanced to 460% for the CS–CaCO3 composites material compared to the CaCO3 or chitosan with only one single component. The coagulation studies in vivo illustrated that the blood clotting time was greatly reduced from 31 s for CaCO3 to 16 s for the CS–CaCO3 composite material. According to the results of the wound healing experiments in rats, it was found that the CS–CaCO3 composite material can promote wound healing. The CS–CaCO3 composite material could accelerate wound healing to a rate of 9 days, compared with 12 days for the CaCO3. The hemostatic activity, biocompatibility, and low cost of CS–CaCO3 composite material make it a potential agent for effective hemostatic and wound healing materials.To get more news about quickclot combat gauze, you can visit rusuntacmed.com official website.
Hemorrhaging is a leading cause of deaths that result from traffic accidents and military conflict [1,2]. In hospitals, hemorrhage causes 15–25% of trauma deaths. A lot of hemostatic materials are used for hemorrhage controlling [3,4], which can be divided into inorganic materials [5,6,7] and organic polymer materials [8]. Inorganic materials include WoundStat, QuikClot, and Combat Gauze and polymer materials include Celox, Celox-D, HemCon, which are all commercially available products for hemostatic wound healing. However, the inorganic materials have many disadvantages, e.g., in the first generation of inorganic hemostatic materials, QuikClot caused high exothermic reactions and induced tissue empyrosis and other abnormal foreign-body reactions [9,10], and another inorganic material, WoundStat, induced thrombus in lungs and vessels [11,12]. Additionally, the poor adhesion of Combat Gauze made more blood loss [13]. Therefore, research is necessary to find more effective hemostatic agents.
Thrombin is an enzyme which can support earlier fibrin generation in the “waterfall reaction” of blood clotting. Calcium ions have the function to form thrombin and then activate the coagulation system. At the same time, intracellular Ca2+ can cause phosphatidyl serines to be exposed on platelet surfaces, and further help to assemble coagulation complexes and amplify the formation of thrombin [14,15]. Ca2+ can also stop bleeding by increasing clot rigidity. Similar to the benefit of Ca2+, CaCO3 also has good biocompatibility and potential for applications in medicine. In traditional Chinese medicine, cuttlebone, a kind of traditional hemostatic material that consists of CaCO3 is orally administered and can rapidly stop bleed [16,17,18,19,20,21]. Accordingly, developed hemostatic materials based on CaCO3 have been investigated for tissue repairing and rapid wound closure [22,23]
Chitosan is an inexpensive natural-origin polymer that has been widely used in clinics for its biodegradability, biocompatibility and antimicrobial activities [24,25]. Chitosan also has been widely investigated because of its hemostatic function [26,27,28,29,30]. The protonated amine groups of chitosan have a static interaction with the negative charge of red blood cells and platelets that induces formation of thrombus [31]. Chitosan also has good water absorption ability to facilitate hemostasis by blood coagulation factors and concentrating platelets [32,33,34]. Some commercially available materials have been developed based on chitosan as hemostatic agents such as Celox, TraumaStat, HemCon and so on. Chitosan-based materials demonstrated effective and safe properties for trauma application [35]. However, chitosan hemostatic materials cannot be used to treat wounds with heavy bleeding, because chitosan materials have no adhesion and may be washed away by blood, or chitosan materials may enter the blood vessels of the wound and cause thrombosis [36].