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The Dollar posted weekly gain due from Covid 19
The dollar posted weekly gains due to fears of spreading waves from the Covid-19 pandemic. The total number of cases in Germany increased by 913 to 173,152 on Thursday and Friday. While the number of dead rose 101 to 7,824 after the country made lockdown relaxation. New cases have also been noted in various countries which loosened lockdown rules, dashing optimism about the recovery of the global economy. To get more news about WikiFX, you can visit wikifx news official website.
With the waning hopes of a global economy recovering quickly, market participants are again after safe haven assets, such as the US dollar. Safe-haven demand increased after renewed tensions between the US and China. President Trump stated that he was reluctant to dialogue with President XI Jinping and said that his party could have cut off relations with China. The pound fell 0.6% last Friday to $ 1.2155, the lowest since March 27, after European Union Brexit negotiator Michel Barnier said on Friday that the third round of talks with Britain was “disappointing”. While the euro also fell after data showing the German economy contracted 2.2% in the 1-2020 quarter. At present the German economy has entered a recession from the 2009 financial crisis.
Spot gold prices touched a 7.5-year high last Friday, while US gold futures rose to a one-month high after disappointing US data. Last Friday's data showed retail sales fell 16.4%, while industrial output fell 11.4%, marking the worst monthly performance for both data because the Covid-19 pandemic nearly paralyzed the US economy. . The price of gold has soared following the escalation of new US-China tensions. Although overshadowed by concerns about renewed tensions between the US and China, oil prices managed to strengthen last week. Sentiment that drives oil prices includes efforts to cut output by oil producing countries. Saudi Arabia said Monday it would cut more production by 1 million bpd in June. Meanwhile, although US President Donald Trump is outraged against China, this can be masked by Chinese data, which led WTI to rise to the $ 30 per barrel area. Data last Friday showed China's industrial output rose 3.9% in April, recovering after falling 1.1% in March.
Oil prices also rose after the number of rigs in the US declined, as well as EIA data that showed US oil reserves fell for the first time in 15 weeks by 745 thousand barrels. On Friday the price of WTI oil rose 6.8% to $ 29.43 a barrel, while Brent rose 4.4% to $ 32.50. During the week WTI rose 19%, while Brent rose 5%. US stock index futures gained amid mixed sentiment after the reopening of the economy around the world was offset by warnings that economic recovery will take a long time. The S&P 500 index rose 0.6%. Meanwhile, Asian stock index futures moved varied. In Asia, the Hong Kong futures index fell, but shares in Japan and Australia strengthened. Focus This Week: Powell, Bailey, Lowe & PMI Data There are three central bank officials who will deliver speeches this week, they are the chairman of the Fed, Jerome Powell, BoE Governor Andrew Bailey, and RBA Governor Phillip Lowe. Another market focus is PMI data services and manufacturing services in the UK and US. Other data that is worth looking at is the US Jobless Claims and the Philly Fed Manufacturing Index. Meanwhile, the Fed will also release its minutes.
The dollar posted weekly gains due to fears of spreading waves from the Covid-19 pandemic. The total number of cases in Germany increased by 913 to 173,152 on Thursday and Friday. While the number of dead rose 101 to 7,824 after the country made lockdown relaxation. New cases have also been noted in various countries which loosened lockdown rules, dashing optimism about the recovery of the global economy. To get more news about WikiFX, you can visit wikifx news official website.
With the waning hopes of a global economy recovering quickly, market participants are again after safe haven assets, such as the US dollar. Safe-haven demand increased after renewed tensions between the US and China. President Trump stated that he was reluctant to dialogue with President XI Jinping and said that his party could have cut off relations with China. The pound fell 0.6% last Friday to $ 1.2155, the lowest since March 27, after European Union Brexit negotiator Michel Barnier said on Friday that the third round of talks with Britain was “disappointing”. While the euro also fell after data showing the German economy contracted 2.2% in the 1-2020 quarter. At present the German economy has entered a recession from the 2009 financial crisis.
Spot gold prices touched a 7.5-year high last Friday, while US gold futures rose to a one-month high after disappointing US data. Last Friday's data showed retail sales fell 16.4%, while industrial output fell 11.4%, marking the worst monthly performance for both data because the Covid-19 pandemic nearly paralyzed the US economy. . The price of gold has soared following the escalation of new US-China tensions. Although overshadowed by concerns about renewed tensions between the US and China, oil prices managed to strengthen last week. Sentiment that drives oil prices includes efforts to cut output by oil producing countries. Saudi Arabia said Monday it would cut more production by 1 million bpd in June. Meanwhile, although US President Donald Trump is outraged against China, this can be masked by Chinese data, which led WTI to rise to the $ 30 per barrel area. Data last Friday showed China's industrial output rose 3.9% in April, recovering after falling 1.1% in March.
Oil prices also rose after the number of rigs in the US declined, as well as EIA data that showed US oil reserves fell for the first time in 15 weeks by 745 thousand barrels. On Friday the price of WTI oil rose 6.8% to $ 29.43 a barrel, while Brent rose 4.4% to $ 32.50. During the week WTI rose 19%, while Brent rose 5%. US stock index futures gained amid mixed sentiment after the reopening of the economy around the world was offset by warnings that economic recovery will take a long time. The S&P 500 index rose 0.6%. Meanwhile, Asian stock index futures moved varied. In Asia, the Hong Kong futures index fell, but shares in Japan and Australia strengthened. Focus This Week: Powell, Bailey, Lowe & PMI Data There are three central bank officials who will deliver speeches this week, they are the chairman of the Fed, Jerome Powell, BoE Governor Andrew Bailey, and RBA Governor Phillip Lowe. Another market focus is PMI data services and manufacturing services in the UK and US. Other data that is worth looking at is the US Jobless Claims and the Philly Fed Manufacturing Index. Meanwhile, the Fed will also release its minutes.
Since WikiFX entered the Nigerian market in Feb. 2020, we have received nearly 900+ complaints against brokers from Nigerian. And these complaints are based on investors real experience. Until now, WikiFX has exposed many forex brokers including Olymptrade, Binomo trade, CRYPTO FX, UniversalFX, aliforex, speedXprofits, EONLINE, IQ option, limpidOptions, GOLDEN FX TRADE, LMFX, OCTAFX, Iron FX, OINVEST etc., among which Olymptrade, Binomo trade, IQ option, and IronFX are complained most.
The forex market in Nigeria is in chaos due to no related laws and regulatory body. This article will present the 4 types of investment fraud in details.To get more news about WikiFX, you can visit wikifx news official website.
The obvious characteristics of forex fraud:
1. Can not withdraw money due to update system of platform.
2. Need to pay COT(cost of transaction )fee before withdrawing.
3. Slippage is seriously out of the normal range.
4. Unable to log into account due to suspension.
5. A non-existent regulatory body. Or the regulatory body uses a limited companys registration number as a regulatory number. Such as “The Financial Commission”, which is an illegal regulatory body.
6.The address showed on brokers website does not match with its registered address. With unreal address and customer contact number, it has potentially high risk of running away.
7.
To earn high profits from Binary options trading combined with bitcoin trading has become the mainstream in the forex field. From many fraud cases, it can be seen that investors still rely on “luck” rather than reliable investment skills. They never consider what the background of a broker is and where the broker come from, on the contrary, they only focus on when they can get high-return profits.
For example, you have 10 dollars BTC and is promised to get double or triple profits in a shorty period time from brokers. And even more exaggerated thing is that you invest 500 dollar, then you can get 5,000 dollars after one week. However, this is a fantasy. Generallythese high-return modelshaveviolated the principle of investment.
The forex market in Nigeria is in chaos due to no related laws and regulatory body. This article will present the 4 types of investment fraud in details.To get more news about WikiFX, you can visit wikifx news official website.
The obvious characteristics of forex fraud:
1. Can not withdraw money due to update system of platform.
2. Need to pay COT(cost of transaction )fee before withdrawing.
3. Slippage is seriously out of the normal range.
4. Unable to log into account due to suspension.
5. A non-existent regulatory body. Or the regulatory body uses a limited companys registration number as a regulatory number. Such as “The Financial Commission”, which is an illegal regulatory body.
6.The address showed on brokers website does not match with its registered address. With unreal address and customer contact number, it has potentially high risk of running away.
7.
To earn high profits from Binary options trading combined with bitcoin trading has become the mainstream in the forex field. From many fraud cases, it can be seen that investors still rely on “luck” rather than reliable investment skills. They never consider what the background of a broker is and where the broker come from, on the contrary, they only focus on when they can get high-return profits.
For example, you have 10 dollars BTC and is promised to get double or triple profits in a shorty period time from brokers. And even more exaggerated thing is that you invest 500 dollar, then you can get 5,000 dollars after one week. However, this is a fantasy. Generallythese high-return modelshaveviolated the principle of investment.
Britain announced an important plan to cut tariffs by 30 billion pounds after Brexit, while also releasing the latest most-favored-nation rate of duty.To get more news about WikiFX, you can visit wikifx news official website.
The British Global Tariff that will replace EUs common external tariffs from January 1st, 2021 centers around the following points:
1.The new British tariff ensures that from January, 2021, 60% of foreign trade will enter the country on WTO terms or through existing preferential access.
2.Britain will promote sustainable economy by cutting tariffs on over 100 different products to support renewable energy, energy efficiency, carbon capture and storage and circular economy. Import tariffs on agricultural produce such as beef and mutton and most of ceramic products will remain unchanged, and a 10% tariff will be applied to automotive.
3.The new tariff plan will be set in pounds and is less complicated than the EU tariffs
The British Global Tariff that will replace EUs common external tariffs from January 1st, 2021 centers around the following points:
1.The new British tariff ensures that from January, 2021, 60% of foreign trade will enter the country on WTO terms or through existing preferential access.
2.Britain will promote sustainable economy by cutting tariffs on over 100 different products to support renewable energy, energy efficiency, carbon capture and storage and circular economy. Import tariffs on agricultural produce such as beef and mutton and most of ceramic products will remain unchanged, and a 10% tariff will be applied to automotive.
3.The new tariff plan will be set in pounds and is less complicated than the EU tariffs
Check your Mega Millions ticket because somebody here in Arizona just
won Tuesday’s $410 million jackpot. It’s a first for Arizona. The
jackpot can be paid out as an an annuity with 30 annual payments or is
worth $319.9 million if collected in a lump-sum, officials said. The
final jackpot amount was slightly higher than the estimated value,
officials said.
The Arizona Lottery says the Circle K at 67th Avenue and Beardsley Road in Glendale sold the ticket. Get more news about 彩票包网开版,you can vist loto98.com
The winning numbers are 1, 5, 9, 10, and 23, plus the gold Mega Ball 22. If those are the numbers you have, the Arizona Lottery suggests signing the back of ticket immediately.Last August, Arizona joined a growing number of states allowing people who win lottery jackpots of $100,000 to remain anonymous forever. The law specifies that winners of Arizona Lottery prizes of $100,000 or more automatically remain anonymous for 90 days but the winners can choose to remain anonymous permanently.
“Every single person that has won that sort of money has opted for that,” Arizona Lottery spokesman John Gilleland said.The Mega Millions jackpot has been rolling since Feb. 11, growing to become the largest prize in a year.
According to the Mega Millions website, 13 tickets matched all five white balls. Nine of those tickets were sold in Florida, Maryland, Michigan, Minnesota, Pennsylvania, and Washington. They’re worth $1 million each. The other four tickets matched the five white balls and the Megaplier. Those tickets are worth $2 million and were sold in Mississippi, New York, and South Carolina. This is the first big Mega Millions prize for the Mississippi Lottery. Founded in August 2018, it’s the newest lottery in the country.
The third prize in the Mega Millions game is $10,000. According to the Mega Millions website, 74 tickets matched four white balls and the Mega Ball. Thirteen of them had the Megaplier option, which doubled the prize to $20,000.
The Arizona Lottery says the Circle K at 67th Avenue and Beardsley Road in Glendale sold the ticket. Get more news about 彩票包网开版,you can vist loto98.com
The winning numbers are 1, 5, 9, 10, and 23, plus the gold Mega Ball 22. If those are the numbers you have, the Arizona Lottery suggests signing the back of ticket immediately.Last August, Arizona joined a growing number of states allowing people who win lottery jackpots of $100,000 to remain anonymous forever. The law specifies that winners of Arizona Lottery prizes of $100,000 or more automatically remain anonymous for 90 days but the winners can choose to remain anonymous permanently.
“Every single person that has won that sort of money has opted for that,” Arizona Lottery spokesman John Gilleland said.The Mega Millions jackpot has been rolling since Feb. 11, growing to become the largest prize in a year.
According to the Mega Millions website, 13 tickets matched all five white balls. Nine of those tickets were sold in Florida, Maryland, Michigan, Minnesota, Pennsylvania, and Washington. They’re worth $1 million each. The other four tickets matched the five white balls and the Megaplier. Those tickets are worth $2 million and were sold in Mississippi, New York, and South Carolina. This is the first big Mega Millions prize for the Mississippi Lottery. Founded in August 2018, it’s the newest lottery in the country.
The third prize in the Mega Millions game is $10,000. According to the Mega Millions website, 74 tickets matched four white balls and the Mega Ball. Thirteen of them had the Megaplier option, which doubled the prize to $20,000.
A sole winning ticket for Tuesday’s $410 million Mega Millions drawing
was sold at a convenience store in a Phoenix suburb, lottery officials
said Wednesday.Get more news about 彩票包网,you can vist loto98.com
The winning ticket was purchased at a Circle K in the city of Glendale, Arizona Lottery spokesman John Gilleland said Wednesday.
The jackpot can be paid out as an an annuity with 30 annual payments or is worth $316.8 million if collected in a lump-sum, Gilleland said.
The winning numbers were 1, 5, 9, 10 and 23, with Mega Ball 22.
Under a 2019 Arizona law, the winner can remain anonymous forever, Gilleland said.
“We may never be able to release the identity,” he said.
The law specifies that winners of Arizona Lottery prizes of $100,000 or more automatically remain anonymous for 90 days but the winners can choose to remain anonymous permanently. The option for permanent anonymity was adopted last year.
“Every single person that has won that sort of money has opted for that,” Gilleland said.
As of Tuesday afternoon, the prize was unclaimed. The ticket was sold at Fast Lane Shell, 1999 E. Ajo Way, near South Kino Parkway, according to Arizona State Lottery officials.
The ticket matched four out of the five numbers and the Powerball number. "This ticket's cash prize would have been $50,000, but since the ticket also had Power Play, the total cash prize tripled to $150,000," officials said.
The winning numbers were 16, 32, 35, 36, 46 and Powerball number 3. The Power Play number was 3. The holder of a Powerball ticket worth more than $136 million has contacted the West Virginia lottery.
But lottery assistant director Randy Burnside says the winner wants to remain anonymous.The ticket that was sold at a convenience store in Hinton was the only winning ticket in the country to match all six numbers drawn June 3.
The winning ticket was purchased at a Circle K in the city of Glendale, Arizona Lottery spokesman John Gilleland said Wednesday.
The jackpot can be paid out as an an annuity with 30 annual payments or is worth $316.8 million if collected in a lump-sum, Gilleland said.
The winning numbers were 1, 5, 9, 10 and 23, with Mega Ball 22.
Under a 2019 Arizona law, the winner can remain anonymous forever, Gilleland said.
“We may never be able to release the identity,” he said.
The law specifies that winners of Arizona Lottery prizes of $100,000 or more automatically remain anonymous for 90 days but the winners can choose to remain anonymous permanently. The option for permanent anonymity was adopted last year.
“Every single person that has won that sort of money has opted for that,” Gilleland said.
As of Tuesday afternoon, the prize was unclaimed. The ticket was sold at Fast Lane Shell, 1999 E. Ajo Way, near South Kino Parkway, according to Arizona State Lottery officials.
The ticket matched four out of the five numbers and the Powerball number. "This ticket's cash prize would have been $50,000, but since the ticket also had Power Play, the total cash prize tripled to $150,000," officials said.
The winning numbers were 16, 32, 35, 36, 46 and Powerball number 3. The Power Play number was 3. The holder of a Powerball ticket worth more than $136 million has contacted the West Virginia lottery.
But lottery assistant director Randy Burnside says the winner wants to remain anonymous.The ticket that was sold at a convenience store in Hinton was the only winning ticket in the country to match all six numbers drawn June 3.
government slows down intersection explosiveness camera study courselawyer popular is late the rollout at intersection driving to fast hidden cameras so that the government ought to get together much more info on the conduct car owners.robert Farnworth asserted thursday your dog modified the man's timeline to trigger some Cheap Authentic Professional Jerseys of the current 140 scarlet lighter intersection hidden cameras to trap speeders received from between late end up to are not forthcoming on the website sooner. you have got 140 intersection digital slr cameras and then there quite a few data and prognosis and even takes time, almost definitely (seeking) much more time then turned out at first anticipated, Farnworth stated.we had arrived launching understand it we announced the fall. that was absolutely span,shell out. and then whatever talking about soon is it obviously likely to be at some time in order to why. requirement to become so as to get begin the process of this eating routine certain point, he explained. which experts claim some time will easily be in 2019. not really traviling to where there's coming to a announcements in such a any time soon, Farnworth put in.the entire postponement has come about as Farnworth ministry wrestles offering concluding where intersections helping put increase video cameras, At how much rates of speed to ticket driver's and ways to share often the sales that have area health systems.executive recent times moved the current 140 purple minimal dslrs that would 24 hour morning such as six hour action signifies and they are event tons of additional statistics how car owners unquestionably are conducting, At everything that data transfer speeds they can be on a journey exactly where there is the most dangerous crossing points can be found.keep various work being done on the existing device, which had been you see, the orange mild intersection spy cameras setting up due to six in order to really 24 tons per day, described Farnworth. Ministry would like to see the actual and even the most severe intersections exist can do what (A improve stanza da letto) maximize wisdom. review articles on the offer long term came after your firm stand out by the ministry thursday that said the technique would prefer to set the limit speed for giving a driving too fast citation by the rate cameras would not be published. which could average individuals wouldn establish obviously if using 10 km/h more than those updated ceiling, or just 30 km/h, undoubtedly turn on the particular digital slr cameras.watch over the dependability of software program, any enforcement limit won't be published, you see, the ministry proclaimed in your firm stand out. agreement due to provincial regulations, It which all delivery staff abide by the released quickness decreases. clarified a person's review, trying to say the problem too quickly to speak about these resources, and has not given virtually any choice by will make-up exeeding the speed limit belonging to the e - adoring coming from the gear.like that has genuinely crossed excellent office yet, cheap authentic jerseys for women he was quoted saying.consistently, The secrecy put up security system alarms as naysayers from your eos cameras, who also say the general public can become aggravated by a fantastic human judgements decrease set in top-secret by ministry authorities, Because it is also revised to achieve politics considerations or even ratchet up the volume of lotto tickets anytime the us govenment standards whole lot more taking.Is a well used NDP look at, which would be to be secretive just as if they are with the proportional reflection referendum, being said opponent head phil Wilkinson. is able to say wheone particularr until this pace threshold will most likely a significant exceeding processed constrain, this modifies humans thinking. the goal really to earn money, except the actual best roadways risk-free. menti one d the digital cameras garnered have the equivalent discernment cops witout a doubt choose to merely citation the most detrimental speeders who? re endangering the rest on the path.are all aware the police application prudence on revving be important and are not looking to obstruct specific traffic that many selling at a secure design even if it a few kilometres speed limit over the, he said.downside to this is the assistance isn't going to have different ethics, referred to Tootill. could well believe in them can certainly offering visibility. And if they were given transparency, in which reveals a pandora box, this puts into wonder if they certainly the proper job from surroundings final results slows. 1990s NDP photos radar regimen exploited a formula in tested the 85th percentile of using the explosiveness committed using street a threshold to inducer a infractions, alleged Tootill. also had been still look and feel predicaments, or even she installed.the us govenment claimed rate webcams when March. it is also renegotiating what companies internet traffic admission return having municipalities to afford the start up in addition to the operational loses of the course. The exact location for schedule cams weren't create.all the time pronounced when you are these crossing points go up there is the just forewarning you must be embarking a backpack, reported Farnworth. Now it is a lot of work however to be performed, And at this time I can any more information than any.
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Glenmark Pharmaceuticals appears to have stolen a march over its
peers after it received regulatory clearance in India for and launched
its version of favipiravir, the antiviral currently being evaluated as
part of treatment options for COVID-19 in several countries including
Japan.To get more news about 259793-96-9, wisepowder official website is the best place for you.
Glenmark’s product, to be sold as FabiFlu, has received emergency use authorization in India for the treatment of mild to moderate COVID-19, the disease caused by the coronavirus. The manufacturing and marketing go-ahead was granted as part of an accelerated approval process, which takes into account disease severity, rarity and the availability of alternative treatments, the firm explained in a presentation. Patients will be required to provide informed consent before initiation of treatment.
Glenmark said the approval terms also require the company to submit updated safety and efficacy data to India’s drug regulator on “a periodic basis. Further, we will be submitting postmarketing surveillance of the first 1,000 patients who access the drug. The CDSCO [Central Drugs Standard Control Organization] has given us three months to submit a final clinical trial report, which we expect to complete in about four weeks from now,” Glenmark told Generics Bulletin sister publication Scrip.
Glenmark’s chair and managing director Glenn Saldanha noted that since FabiFlu is orally administered, it serves as a more convenient treatment option over other intravenously administered medications. “Glenmark will work closely with the government and medical community to make FabiFlu quickly accessible to patients across the country,” Saldanha added.
The product, which acts as an RNA polymerase inhibitor, is available as a 200mg tablet and priced at INR3,500 ($45.90) for a pack of 34 tablets. While pricing may appear rational, some industry experts said that treatment entails a significant pill burden, given the day-one dose requirement of 1,800mg twice-daily and then 800mg twice-daily from day two onwards, for a maximum 14 days.
“This would imply 18 tablets are to be taken on day one, and that’s a challenge, but higher-dose tablets may be on the anvil,” one expert told Scrip.Glenmark has been conducting Phase III trials with favipiravir as a monotherapy option for COVID-19. The study evaluated efficacy and safety plus standard of care versus standard of care alone in mild to moderate disease and involved 150 patients at 11 sites across India.
On how the clinical improvement/recovery rate in the study compared to other global trials, the Mumbai-based firm said that, globally, COVID-19 patients treated with favipiravir have shown positive outcomes such as reduced clinical symptoms and quicker disease recovery within one week. “Glenmark’s clinical trial findings are in line with global data, with most patients showing clinical improvements within the first seven days of treatment initiation,” the company said.
There is significant global development activity around favipiravir for COVID-19 and Glenmark highlighted that around 18 clinical trials involving over 3,000 subjects are underway in countries including India, the US, Canada, Italy, China, France and the UK.
Glenmark’s product, to be sold as FabiFlu, has received emergency use authorization in India for the treatment of mild to moderate COVID-19, the disease caused by the coronavirus. The manufacturing and marketing go-ahead was granted as part of an accelerated approval process, which takes into account disease severity, rarity and the availability of alternative treatments, the firm explained in a presentation. Patients will be required to provide informed consent before initiation of treatment.
Glenmark said the approval terms also require the company to submit updated safety and efficacy data to India’s drug regulator on “a periodic basis. Further, we will be submitting postmarketing surveillance of the first 1,000 patients who access the drug. The CDSCO [Central Drugs Standard Control Organization] has given us three months to submit a final clinical trial report, which we expect to complete in about four weeks from now,” Glenmark told Generics Bulletin sister publication Scrip.
Glenmark’s chair and managing director Glenn Saldanha noted that since FabiFlu is orally administered, it serves as a more convenient treatment option over other intravenously administered medications. “Glenmark will work closely with the government and medical community to make FabiFlu quickly accessible to patients across the country,” Saldanha added.
The product, which acts as an RNA polymerase inhibitor, is available as a 200mg tablet and priced at INR3,500 ($45.90) for a pack of 34 tablets. While pricing may appear rational, some industry experts said that treatment entails a significant pill burden, given the day-one dose requirement of 1,800mg twice-daily and then 800mg twice-daily from day two onwards, for a maximum 14 days.
“This would imply 18 tablets are to be taken on day one, and that’s a challenge, but higher-dose tablets may be on the anvil,” one expert told Scrip.Glenmark has been conducting Phase III trials with favipiravir as a monotherapy option for COVID-19. The study evaluated efficacy and safety plus standard of care versus standard of care alone in mild to moderate disease and involved 150 patients at 11 sites across India.
On how the clinical improvement/recovery rate in the study compared to other global trials, the Mumbai-based firm said that, globally, COVID-19 patients treated with favipiravir have shown positive outcomes such as reduced clinical symptoms and quicker disease recovery within one week. “Glenmark’s clinical trial findings are in line with global data, with most patients showing clinical improvements within the first seven days of treatment initiation,” the company said.
There is significant global development activity around favipiravir for COVID-19 and Glenmark highlighted that around 18 clinical trials involving over 3,000 subjects are underway in countries including India, the US, Canada, Italy, China, France and the UK.
As Glenmark Pharmaceuticals launched antiviral drug Favipiravir for the
treatment of mild to moderate COVID-19 cases, medical experts on
Saturday cautioned against seeing it as a "magic bullet" to treat the
deadly virus but said it will be helpful as it can be orally
administered and reduce viral load.To get more news about 259793-96-9, wisepowder official website is the best place for you.
They said the drug's real efficacy would be known in the coming months.
Glenmark Pharmaceuticals said it has launched antiviral drug Favipiravir, under the brand name FabiFlu, for the treatment of patients with mild to moderate COVID-19 at a price of about Rs 103 per tablet.FabiFlu is the first oral Favipiravir-approved medication in India for the treatment of COVID-19, it said in a statement.
"This drug was already being used in Japan for influenza. They have been using it in COVID-19 patients also. Even China was using it and Russia had also given permission in May to use it. Antiviral drugs like Remdesivir and Favipiravir are not specific to COVID-19 but were being used for influenza," said Dr Vikas Maurya, Director, Department of Pulmonology and Sleep Disorders, Fortis Hospital, Shalimar Bagh.
He said studies found that there was some benefit of Favipiravir in COVID-19 treatment and that is why it has now been launched in India as well.Dr Maurya said with COVID-19 cases rising, the launching of the drug comes as a relief.
"It is not a magic bullet as it is not the only thing we have to give. This is not a specific drug made for COVID-19 and has been found to be useful, but how much it will be useful we will have to see. Real efficacy will be known when administered on a large scale," he told PTI.
"Best thing is that it is an oral drug, while Ramdesiver is an intravenous drug. It (Favipiravir) can be even taken at home. So even if it is giving some benefit, it will be quite useful," Dr Maurya said.
Noted city-based lung surgeon Dr Arvind Kumar said he does not believe that any of these antiviral drugs like Remdisiver or Favipiravir will be game changers.
"If at all ''game changer'' can be used, it is for dexamethasone which has shown a significant reduction in mortality and is available cheaply," he said.There are so many medications available and Favipiravir will also help some patients, added Dr Kumar, who works at Sir Ganga Ram Hospital.
The Favipiravir drug will be available as a 200 mg tablet at a maximum retail price of Rs 3,500 for a strip of 34 tablets, Glenmark Pharmaceuticals said.It is a prescription-based medication with recommended dose being 1,800 mg twice daily on day one, followed by 800 mg twice daily up to day 14, it added.The tablets are being produced by the company at its Baddi facility in Himachal Pradesh. The drug will be available both through hospitals and the retail channel, Glenmark said.
They said the drug's real efficacy would be known in the coming months.
Glenmark Pharmaceuticals said it has launched antiviral drug Favipiravir, under the brand name FabiFlu, for the treatment of patients with mild to moderate COVID-19 at a price of about Rs 103 per tablet.FabiFlu is the first oral Favipiravir-approved medication in India for the treatment of COVID-19, it said in a statement.
"This drug was already being used in Japan for influenza. They have been using it in COVID-19 patients also. Even China was using it and Russia had also given permission in May to use it. Antiviral drugs like Remdesivir and Favipiravir are not specific to COVID-19 but were being used for influenza," said Dr Vikas Maurya, Director, Department of Pulmonology and Sleep Disorders, Fortis Hospital, Shalimar Bagh.
He said studies found that there was some benefit of Favipiravir in COVID-19 treatment and that is why it has now been launched in India as well.Dr Maurya said with COVID-19 cases rising, the launching of the drug comes as a relief.
"It is not a magic bullet as it is not the only thing we have to give. This is not a specific drug made for COVID-19 and has been found to be useful, but how much it will be useful we will have to see. Real efficacy will be known when administered on a large scale," he told PTI.
"Best thing is that it is an oral drug, while Ramdesiver is an intravenous drug. It (Favipiravir) can be even taken at home. So even if it is giving some benefit, it will be quite useful," Dr Maurya said.
Noted city-based lung surgeon Dr Arvind Kumar said he does not believe that any of these antiviral drugs like Remdisiver or Favipiravir will be game changers.
"If at all ''game changer'' can be used, it is for dexamethasone which has shown a significant reduction in mortality and is available cheaply," he said.There are so many medications available and Favipiravir will also help some patients, added Dr Kumar, who works at Sir Ganga Ram Hospital.
The Favipiravir drug will be available as a 200 mg tablet at a maximum retail price of Rs 3,500 for a strip of 34 tablets, Glenmark Pharmaceuticals said.It is a prescription-based medication with recommended dose being 1,800 mg twice daily on day one, followed by 800 mg twice daily up to day 14, it added.The tablets are being produced by the company at its Baddi facility in Himachal Pradesh. The drug will be available both through hospitals and the retail channel, Glenmark said.
Fujifilm is ramping up production of its antiviral treatment
favipiravir, one of many approved drugs being tested as a possible
treatment for COVID-19. Phase III clinical trials are ongoing in Japan,
and the government has ordered 2 million treatment courses. In the US,
Fujifilm started Phase II trials earlier this month.To get more news
about Favipiravir, wisepowder official website is the best place for you.
Favipiravir, which Fujifilm sells under the brand name Avigan, has been approved in Japan since 2014 to treat influenza and other viral strains that don’t respond to other drugs. “Avigan tablets are expected to have efficacy against infection with the new coronavirus in view of its characteristic mechanism of action,” says a Fujifilm spokesperson,although the company has yet to present evidence of efficacy.
The Japanese government stated its preference for Avigan to be made in Japan using domestically produced materials. Toyama Chemical, the Fujifilm subsidiary that developed Avigan, will fulfill part of its requirement for a key intermediate, diethyl malonate, from the chemical producer Denka. The firm will restart a plant in Niigata Prefecture that it had closed in 2017 because of global oversupply of the material. The facility was not dismantled and should be able to resume full operations in late May, according to a Denka spokesperson.In addition, Fujifilm will boost production of intermediates at its Wako Pure Chemical subsidiary and establish partnerships with other raw material suppliers.
Fujifilm expects to complete small Phase III trials in Japan, involving 100 people, in June. In the US, Phase II trials with 50 people will be conducted at Brigham and Women’s Hospital, Massachusetts General Hospital, and the University of Massachusetts Medical School. Italy and China launched clinical trials of the antiviral in March.
According to the Fujifilm spokesperson, human trials so far have not uncovered any adverse reactions. The drug has not been tested on pregnant women, however, because preclinical studies indicated possible harm to fetuses.
Like Gilead Sciences’ remdesivir, another antiviral being tested against COVID-19, favipiravir is a selective inhibitor of the RNA polymerase involved in viral replication. Animal studies showed that it’s effective against influenza as well as West Nile virus, yellow fever, foot-and-mouth disease, and other viruses, Fujifilm says.
The firm notes that thus far the Japanese government is the only group that has ordered large quantities of favipiravir to use against COVID-19. The World Health Organization did not include favipiravir among the four existing drugs it is testing against the disease in a multinational trial.
Favipiravir, which Fujifilm sells under the brand name Avigan, has been approved in Japan since 2014 to treat influenza and other viral strains that don’t respond to other drugs. “Avigan tablets are expected to have efficacy against infection with the new coronavirus in view of its characteristic mechanism of action,” says a Fujifilm spokesperson,although the company has yet to present evidence of efficacy.
The Japanese government stated its preference for Avigan to be made in Japan using domestically produced materials. Toyama Chemical, the Fujifilm subsidiary that developed Avigan, will fulfill part of its requirement for a key intermediate, diethyl malonate, from the chemical producer Denka. The firm will restart a plant in Niigata Prefecture that it had closed in 2017 because of global oversupply of the material. The facility was not dismantled and should be able to resume full operations in late May, according to a Denka spokesperson.In addition, Fujifilm will boost production of intermediates at its Wako Pure Chemical subsidiary and establish partnerships with other raw material suppliers.
Fujifilm expects to complete small Phase III trials in Japan, involving 100 people, in June. In the US, Phase II trials with 50 people will be conducted at Brigham and Women’s Hospital, Massachusetts General Hospital, and the University of Massachusetts Medical School. Italy and China launched clinical trials of the antiviral in March.
According to the Fujifilm spokesperson, human trials so far have not uncovered any adverse reactions. The drug has not been tested on pregnant women, however, because preclinical studies indicated possible harm to fetuses.
Like Gilead Sciences’ remdesivir, another antiviral being tested against COVID-19, favipiravir is a selective inhibitor of the RNA polymerase involved in viral replication. Animal studies showed that it’s effective against influenza as well as West Nile virus, yellow fever, foot-and-mouth disease, and other viruses, Fujifilm says.
The firm notes that thus far the Japanese government is the only group that has ordered large quantities of favipiravir to use against COVID-19. The World Health Organization did not include favipiravir among the four existing drugs it is testing against the disease in a multinational trial.
Introduction An outbreak of severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2) was reported in Wuhan, China in mid-December
2019, and declared a pandemic by the World Health Organization (WHO) on
March 11, 2020. Due to the unknown nature of the disease and the lack of
specific drugs, several potential treatments were used for patients.
This systematic review and meta-analysis will evaluate studies of the
effects of Favipiravir in COVID-19 pneumonia. Methods and analysis We
will search electronic databases including LitCovid hub, PubMed, Scopus,
ISI web of Sciences, Cochrane, and Embase using keywords related to
COVID-19 and Favipiravir. To get more news about Favipiravir, wisepowder official website is the best place for you.
We will search the reference lists of all included studies and reviews. We will also search for clinical trial registries, such as clinicaltrial.gov for the ongoing clinical trials. Two investigators (MAZ and SH) will independently screen titles, abstracts, and full-text of included studies based on eligibility criteria. These investigators will also independently extract data and appraise the quality of studies. All potential discrepancies will be resolved through consultation with the third reviewer. Data synthesis will be conducted using the Review Manager software (version 5.3) or CMA (version 2). Statistical heterogeneity will be assessed using a standard I2 test. A funnel plot, Egger test, and Begg test will be used for asymmetry to explore possible publication bias. Ethics and dissemination The findings of this systematic review with proportional meta-analysis will help to identify the safety and efficacy of Favipiravir for COVID-19 patients. Knowledge gained from this research will also assist physicians in selecting better treatment options and developing a guideline in this field.
All relevant ethical guidelines have been followed; any necessary IRB and/or ethics committee approvals have been obtained and details of the IRB/oversight body are included in the manuscript.
I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance).
I have followed all appropriate research reporting guidelines and uploaded the relevant EQUATOR Network research reporting checklist(s) and other pertinent material as supplementary files, if applicable.
We will search the reference lists of all included studies and reviews. We will also search for clinical trial registries, such as clinicaltrial.gov for the ongoing clinical trials. Two investigators (MAZ and SH) will independently screen titles, abstracts, and full-text of included studies based on eligibility criteria. These investigators will also independently extract data and appraise the quality of studies. All potential discrepancies will be resolved through consultation with the third reviewer. Data synthesis will be conducted using the Review Manager software (version 5.3) or CMA (version 2). Statistical heterogeneity will be assessed using a standard I2 test. A funnel plot, Egger test, and Begg test will be used for asymmetry to explore possible publication bias. Ethics and dissemination The findings of this systematic review with proportional meta-analysis will help to identify the safety and efficacy of Favipiravir for COVID-19 patients. Knowledge gained from this research will also assist physicians in selecting better treatment options and developing a guideline in this field.
All relevant ethical guidelines have been followed; any necessary IRB and/or ethics committee approvals have been obtained and details of the IRB/oversight body are included in the manuscript.
I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance).
I have followed all appropriate research reporting guidelines and uploaded the relevant EQUATOR Network research reporting checklist(s) and other pertinent material as supplementary files, if applicable.