User blogs

Product Name: BETA-NICOTINAMIDE MONONUCLEOTIDE
Synonyms: BETA-NMN;BETA-NICOTINAMIDE MONONUCLEOTIDE;BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE;NMN;NICOTINAMIDE-1-IUM-1-BETA-D-RIBOFURANOSIDE 5′-PHOSPHATE;NICOTINAMIDE RIBOTIDE;NICOTINAMIDE MONONUCLEOTIDE;3-(aminocarbonyl)-1-(5-O-phosphonato-beta-D-ribofuranosyl)pyridinium
CAS: 1094-61-7
MF: C11H15N2O8P
MW: 334.22
EINECS: 214-136-5
Product Categories: Amines;Aromatics;Bases & Related Reagents;Intermediates & Fine Chemicals; Derivatives;Nucleotides;Pharmaceuticals
Storage temp. 2-8°C
Chemical Properties : White Solid
Usage A product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice . It also enhances hepatic sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation . beta-Nicotinamide mononucleotide powder
β-Nicotinamide mononucleotide Description

Nicotinamide mononucleotide (NMN), a product of the NAMPT reaction and a key NAD+ intermediate, ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. NMN also enhances hepatic sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation. NMN is used for studying binding motifs within RNA aptamers and ribozyme activation processes involving β-nicotinamide mononucleotide (β-NMN)-activated RNA fragments. It is to be used for research only.
Beta-Nicotinamide Mononucleotide Application

The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca2+ signaling pathways. NMNAT (EC 2.7.7.1) is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD.

NMNAT1 is the most widely expressed of three orthologous genes with nicotinamide-nucleotide adenylyltransferase (NMNAT) activity. Genetically engineered mice lacking NMNAT1 die during early embryogenesis, indicating a critical role of this gene in organismal viability.[citation needed] In contrast, mice lacking NMNAT2, which is expressed predominantly in neural tissues, complete development but die shortly after birth. However, NMNAT1 is dispensable for cell viability, as homozygous deletion of this gene occurs in glioblastoma tumors and cell lines. NMNAT enzymatic activity is probably essential at the cellular level, as complete ablation of NMNAT activity in model organisms leads to cellular inviability.

One clinical trial described optimum pramiracetam dosage at 100mg per Kg body weight, whereas pramiracetam was 15mg/ Kg body weight, effectively up to 7 times stronger.
Regular doses of pramiracetam are one tablet (600mg each) once or twice daily (see notes at base of Nootropic section).
Remember that all Nootropics are synergistic with each other and with other brain nutrition products, (for example: choline, DMAE, Hydergine, Centrophenoxineetc.). When combining these products the individual doses may have to be reduced in order to avoid possible side effects of nausea and headaches.

Additional Info.
Payment:Western union,Money gram,T/T,Bitcoin
Shipment:HKEMS,EMS,FedEx,TNT,DHL,UPS,Aramex
Export Markets:Global
Delivery:5-7 Working Days Door to Door
Certification:SGS
Brand Name:Mengfeis
Origin:China
Packing:according to the customer request
Production Capacity:3600kg/Month

Best Price Provide Galantamine Powder

galantamine nootropic is natural extracted from Lycoris radiate, is a tertiary alkaloid derived from snowdrop and closely related species.
Galanthamine acts as a reversible competitive acetylcholinesterase (AChE) inhibitor, while acts weaker on butyrylcholinesterase (BuChE).
Galanthamine is used in the treatment of disorders of the central nervous system and may be used as an antidote to nonpolarizing muscle relaxants.Galantamine hydrobromide is a white to almost white powder; sparingly soluble in water; insoluble chloroform, ether and alcohol.

Function of Galantamine
Galanthamine is the anti-cholinesterase, weak effect.
Galantamine has strong effect to the central nervous system through the blood brain barrier.
Galantamine mainly cures the infantile paralysis sequelae, sweeny and myasthenia gravis
pseudoparalytica, etc.
Galantamine also can be applied to puerilism, posttraumatic apoplexy, polyneuritis and radiculitis.

Clinic function: mainly used in myasthenia gravis, poliovirus quiescent stage and sequela, also in polyneuritis, funiculitis and sensorimotor barrier caused by nervous system disease or traumatism. Galantamine major used in Alzheimer’s disease, has the principal function for dement and dysmnesia caused by organic brain damage.
Application of Galantamine
Galantamine is the anti-cholinesterase, weak effect. Galantamine has strong effect to the central nervous system through the blood brain barrier. Galantamine mainly cures the infantile paralysis sequelae, sweeny and myasthenia gravis pseudoparalytica, etc. Galantamine also can be applied to puerilism, posttraumatic apoplexy, polyneuritis and radiculitis.

99% Nootropics Powder Galantamine for Enhance Memoery

galantamine powder is natural extracted from Lycoris radiate, is a tertiary alkaloid derived from snowdrop and closely related species.
Galanthamine acts as a reversible competitive acetylcholinesterase (AChE) inhibitor, while acts weaker on butyrylcholinesterase (BuChE).
Galanthamine is used in the treatment of disorders of the central nervous system and may be used as an antidote to nonpolarizing muscle relaxants.Galantamine hydrobromide is a white to almost white powder; sparingly soluble in water; insoluble chloroform, ether and alcohol..

Application of Galantamine
Galantamine is the anti-cholinesterase, weak effect. Galantamine has strong effect to the central nervous system through the blood brain barrier. Galantamine mainly cures the infantile paralysis sequelae, sweeny and myasthenia gravis pseudoparalytica, etc. Galantamine also can be applied to puerilism, posttraumatic apoplexy, polyneuritis and radiculitis.
Function of Galantamine
Galanthamine is the anti-cholinesterase, weak effect.
Galantamine has strong effect to the central nervous system through the blood brain barrier.
Galantamine mainly cures the infantile paralysis sequelae, sweeny and myasthenia gravis pseudoparalytica, etc.
Galantamine also can be applied to puerilism, posttraumatic apoplexy, polyneuritis and radiculitis.

Clinic function: mainly used in myasthenia gravis, poliovirus quiescent stage and sequela, also in polyneuritis, funiculitis and sensorimotor barrier caused by nervous system disease or traumatism. Galantamine major used in Alzheimer’s disease, has the principal function for dement and dysmnesia caused by organic brain damage.

Product name: Coluracetam
Specification: 99%
CAS No.: 135463-81-9
Appearance: White powder
Molecular Formula: C19H23N3O3
Molecular Weight: 341.4042
Coluracetam is a nootropic drug of the racetam family. Coluracetam was initially developed and tested by the Mitsubishi Tanabe Pharma Corporation for Alzheimer’s disease. After the drug failed to reach endpoints in its clinical trials it was in-licensed by BrainCells Inc for investigations into major depression disorder (MDD), after being awarded a “Qualifying Therapeutic Discovery Program Grant” by the state of California. Findings from its Phase 2a clinical trials have suggested that it would be an ideal medication for co-morbid MDD with generalized anxiety disorder (GAD). BrainCells Inc is currently out-licensing the drug for this purpose. It may also have potential use in prevention and treatment of ischemic retinopathy and retinal and optic nerve injury.

Memory and Learning

Coluracetam is shown to improve cognitive function and memory in rats, and in theory, the same results are expected in human beings. A study conducted by BrainCells Inc, showed a memory improvement in rats who were given substance AF64A (a neuron-specific neurotoxin) for 8 days along with Coluracetam in 3mg doses. These rats were put through the standardized Morris Water Maze to mark their ability to get through it, and even up to 72 hours after the last 8mg dose, they were still able to. Another key finding of this study was that the results were still apparent 3 days after the last dose, even though the serum concentration of Coluracetam was negligible.

Depression and Anxiety

BrainCells Inc, found that a dosage of 240mg (split into three daily doses of 80mg) was useful in treating major depression co-morbid with GAD (generalized anxiety disorder). However, the differences were most pronounced in those who didn’t find relief in using standard antidepressants. After one dose, there were no noticeable differences, but after 2 doses at 80mg, 36% had improved scores during a depression assessment test.

Eyesight

Coluracetam has been associated with optic benefits such as enhanced color vision, recognition and vividness. Although there isn’t any conclusive evidence to support the mechanisms behind this benefit, experts believe that Coluracetam works in the part of the brain that runs visual processes.

Dosage

Since the study subjects were rats, there aren’t any recommended human dosages, but there is a general guideline for conversion.In rats, the dosage ranged between 1 mg/kg and 10 mg/kg per day. By using allometric scaling, the dose becomes 2.9 mg/kg in humans, so the average dose should not exceed 203.5 mg daily for someone in a typical weight class.

There isn’t very much information to indicate toxicity of Coluracetam, although doses given at the above increments showed no negative side effects. If you haven’t used a nootropic before, you may develop headache after use, which is a common in first time users. By stacking the Coluracetam with Choline, you’ll reduce this risk.

CLA + Carnitine is BPI Health’s #1 Weight Loss Formula. CLA and Carnitine are two very popular ingredients that have been clinically studied for their roles in weight management. CLA and Carnitine are designed to work together to help burn stored body fat, converting it to energy. CLA + CARNITINE is a non-stimulant powder powder that can be taken throughout the day or paired with a powerful fat burner to enhance its effects and speed fat burning and may also help boost athletic performance. CLA + CARNITINE is sugar free and can be added to any pre workout to enhance benefits or be taken alone as part of a healthy weight loss and lean muscle building program.Glycine Propionyl-L-Carnitine powder
Safety Warning
Warnings: Not intended for use by persons under age 18. Do not exceed recommended dose. Get the consent of a licensed physician before using this product, especially if you are taking medication, have a medical condition, you are pregnant, nursing or thinking about becoming pregnant. DISCONTINUE USE TWO WEEKS PRIOR TO SURGERY. KEEP THIS PRODUCT AND ALL SUPPLEMENTS OUT OF THE REACH OF CHILDREN.
Ingredients
CLA MATRIX (Proprietary blend) 2.5 g Safflower Oil Powder (seed), Avocado Oil Powder (fruit), Coconut Oil Powder (fruit), Providing CLA (Conjugated Linoleic Acid) Carnitine (as Carnitine Silicate, Glycine Propionyl L-Carnitine, L-Carnitine Tartrate) Natural and artificial flavors, citric acid, malic acid, maltodextrin, silica, sucralose, acesulfame k, and FD&C Blue No. 1.

Product Name: Lorcaserin HCL powder
English name: Lorcaserin hydrochloride
English Synonyms: (1R) -8-Chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine hydrochloride; APD 356; APD-356; UNII-0QJF08GDPE; Lorcaserin HCl; (R) – 1H-3-Benzazepine, 8-Chloro-2,3,4,5-Tetrahydro-1-Methyl-, Hydrochloride
CAS: 846589-98-8
Formula: C11H14ClN · ClH
MW: 232.1525
Molecular Structure:
Assay:96.21%
Appearance:white powder
Boiling point : 288.125°C at 760 mmHg
Flash point : 128.054°C
Product usage : Medicine reducing weight and antidepressants

Description:
Belviq(Lorcaserin hydrochloride) is an FDA-approved prescription weight-loss medication that, when used with diet and exercise, can help some overweight? adults with a weight-related medical problem, or obese adults, lose weight and keep it off. It is not known if BELVIQ when taken with other prescription, over-the-counter, or herbal weight-loss products is safe and effective. It is not known if BELVIQ changes your risk of heart problems, stroke, or death due to heart problems or stroke.

Centrophenoxine, according to Wikipedia, is an ester of dimethylethanolamine (DMAE) and 4-chlorophenoxyacetic acid (pCPA). DMAE is a natural substance, found especially in fish. pCPA is a synthetic compound that resembles a variety of plant hormones called auxins. Centrophenoxine is a Cholinergic compound with a DMAE (Dimethylaminoethanol) component, and acts as a better absorbed transporter of DMAE into the brain. It is sold under the brand name Lucidril but can easily be bought over the counter or online with the names as Centro, meclofenoxate,etc.Nootropics powder
Centrophenoxine is synthesized from DMAE who is a natural chemical that has been shown to improve areas of cognition and mood.

Centrophenoxine vs DMAE

One thing for sure is that Centrophenoxine is much stronger than DMAE as a nootropic. This is likely due to a higher bioavailability of Centrophenoxine or a difference in how it is metabolized in the liver. If you are taking DMAE as a choline source, consider switching to Centrophenoxine as it is known to be more powerful as a nootropic substance.
Both substances are broken down in the liver. The liver metabolizes both substances and breaks them down into choline or phospholipid molecules. DMAE has been suggested to have limited effectiveness because the choline molecules are charged and therefore have limited effectiveness in getting to the brain.

Benefits of taking Centrophenoxine supplements
From the introduction of Wikipeida, centrophenoxine has been clinically shown to improve memory, have a mentally stimulating effect, and improve general cognition. centrophenoxine also increases cellular membrane phospholipids.
Centrophenoxine does not just help improve the memory, but also aids in protecting memory and reversing the effects of aging on the brain. Centrophenoxine increases RNA which are used by neurons to create protein which is used to encode memory and mend damaged cells in the brain.

Pharmaceutical API 99% Nootropic Drugs Powder Centrophenoxine

Centrophenoxine can enhance unique physical and cognitive properties. Centrophenoxine improves both the functioning and appearance of cells in your brain and body by helping to rid them of waste products and by improving the composition of cellular membranes. Centrophenoxine can thus be considered both a cognitive enhancer and an anti-aging supplement.

Recommended Dosage: 250-500mg
Directions: Centrophenoxine is water soluble. Recommended to take with food. Do not use if you are pregnant/breastfeeding.

It is synthesized from DMAE. DMAE is a natural chemical that has been shown to improve areas of cognition and mood. DMAE’s exact method of action is slightly disputed. Some see it as a precursor to Acetylcholine but others contest this as choline molecules broken down from DMAE are not believed to cross the blood-brain-barrier efficiently.
It is reported that one in three people over the age of 70 experience memory impairment. But even if you are not close to that age yet, you can take steps now to improve your memory now and protect it in the future. Such is the promise of Centrophenoxine as a Nootropic.

Centrophenoxine is one of the best Choline supplements that you can use today. The Choline in the compound actually works as a precursor to Acetylcholine, which is a very strong chemical known as a neurotransmitter.

Acetylcholine is most typically associated with increased brain plasticity which means you can create new connections between neurons more easily. It is also thought to be involved in key cognitive processes, especially memory formation and neuromuscular control.

We need choline from foods that we eat in order to produce acetylcholine, but most people do not reach the recommended daily intake of 550 mg per day. One study published in the journal Nutrition Reviews found that only 10% of the population receives enough of this compound from their diet.

If you are using nootropic supplements like those from the Racetam family (such as Aniracetam or Piracetam), you will likely need more than the advised intake for this supplement to ensure that you get the most out of your nootropics. This is why stacking Piracetam with Centrophenoxine or other choline sources like Alpha GPC and Citicoline is so common.

Centrophenoxine can increase acetylcholine levels, helping to optimize thought processes like those related to memory and reasoning.

Centrophenoxine has also been researched to play a crucial role in anti-aging for your brain. Tests show that this supplement actually helps to improve symptoms such as age related confusion, memory loss, and lack of concentration.

As we age, potassium deposit accumulate in the brain. Centrophenoxine is capable of reversing this and ridding the body of excessive potassium which can actually improve the electrical conductance of your brain. This means signals are able to travel through your neural circuits at a faster rate.

Additionally, a regular dose of Centrophenoxine powder is able to reduce and reverse lipofuscin build up in your brain cells. Lipofuscin is also recognizable as those brown spots on the skin that we tend to develop as we age. It might surprise you that those spots representing waste materials also develop in your brain, but Centrophenoxine can prevent this.

This also accentuates the role of Centrophenoxine as an anti-oxidant. Not only is it effective in removing a number of toxins and poisons from the brain and body but it also helps to eliminate free radicals which can be very damaging to the brain.

Safe Shipping Nootropics Galantamine Hydrobromide Powder Samrt Research CAS

Galantamine Hydrobromide mainly for the treatment of poliomyelitis (poliomyelitis) sequelae, muscle atrophy and myasthenia gravis. Can also be used for children with cerebral palsy, traumatic sensory dyskinesia, polyneuritis and spinal nerve root inflammation.
Galantamine belongs to a class of drugs called cholinesterase inhibitors. A class of drugs refers to medications that work similarly. They have a similar chemical structure and are often used to treat similar conditions.

The cause of Alzheimer’s disease isn’t fully understood. People with this disease have low amounts of a chemical acetylcholine in their brains. A decreased amount of acetylcholine has been linked to dementia. Galantamine works to prevent the breakdown of acetylcholine. This increases the concentration of the chemical in the brain, and may help decrease the symptoms of dementia.
This drug may not work as well when Alzheimer’s disease gets worse. There is no evidence that galantamine prevents Alzheimer’s disease from getting worse.
Galantamine Hydrobromid Application:
This product is anticholinesterase drugs, a weaker anticholinesterase role, through the blood-brain barrier, so the role of the central nervous system is relatively strong. The obstruction of nerve and muscle conduction recovery, improve the various peripheral neuromuscular disorders paralysis.

The treatment of a wide range of less toxic, more tolerable patients. Clinical mainly for the treatment of poliomyelitis (poliomyelitis) sequelae, muscle atrophy and myasthenia gravis. Can also be used for children with cerebral palsy, traumatic sensory dyskinesia, polyneuritis and spinal nerve root inflammation.