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NSI-189 is a benzylphiperizine-aminiopyridine, nootropic and neurogenic research chemical created by Neuralstem, Inc. that was derived from pyrazine and nicotinamide. Studies have shown that it stimulates neurogenesis of human hippocampus-derived neural stem cells in vivo and vitro. In healthy adult mice, NSI-189 has been shown to increase the hippocampal volume by 20% and reverse behavioral symptoms in mouse depression models, meaning at the source it could address depression. The hippocampus is responsible for spatial navigation, along with the consolidation of information from short-term memory to long-term memory.NSI 189 phosphate powder
The chemical entity stimulates new neuron growth in the hippocampus, which is an area of the brain that is believed to be contributory in conditions such as post-traumatic stress disorder (PTSD), Alzheimer's disease, and major depressive disorder (MDD).

Tests have shown that NSI-189 significantly improved behavioral responses that are associated with depression . In humans it may counter hippocampal atrophy which is seen in disorders such as MDD, reversing their symptoms. A phase 1B randomized, double-blind, placebo-controlled, multiple-dose escalation study conducted over a 28 day period showed behavioral efficacy in 24 patients who were orally administered NSI-189 . The efficacy measurements showed a clinically meaningful reduction in cognitive and depressive symptoms across all measures, and appeared to persist over time during follow up for the efficacy assessments which included the Clinical Global Impression - Improvement (CGI-I), Montgomery-Aserb Depression Rating Scale (MADRS), Cognitive and Physical Functioning Questionnaire (CPFQ, and the Symptoms of Depression Questionnaire (SDQ).
buzai232 Sep 1 '19, 12:10AM
Nootropics Powder Nsi-189 Nsi 189 for Antidepressant drug CAS 1270138-41-4



NSI189 powder is an experimental antidepressant. Neuralstem, Inc. is currently testing it for use in major depression, in addition to treating cognitive impairments, and brain degeneration. It may induce specific brain regeneration.
NSI-189 is most likely selective only to two nervous system controlling regions in the brain (hippocampus, subventricular zone)
Usage:
1) May Improve Depression
NSI-189 showed promise treating depression and cognitive impairment in a study (double-blind randomized controlled trial) consisting of 24 people split into these three groups :

40 mg once a day or placebo
80 mg (40 mg twice a day) or placebo
120 mg (40 mg three times a day) or placebo
The NSI-189 group had significant improvements in depression symptoms compared to the control group starting from day 28 up to the follow-up (day 84). However, clinical significance was only shown in self-rating scales .

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2) May Benefit Stroke Patients
Since it can increase nerve cell formation (neurogenesis), NSI-189 shows promise as a potential therapy for those that experienced a stroke to improve brain structure and function .

Scientists gave rats NSI-189 6 hours after an induced stroke. NSI treatment that continued for 12 weeks post-stroke resulted in significant improvements in brain and motor deficits. This improvement lasted 24-weeks post-therapy .

NSI also helped remodel rat's brains post-stroke and showed an overall improvement in the initial six months .

3) May Improve Cognitive Function
In a study of 24 depression patients (double-blind randomized controlled trial), NSI-189 increased self-reported cognitive function .

More studies need to be done to determine if this was due to the reduction of depression symptoms, or a result of overall neurogenesis .

4) May Help Increase Neuron Formation
The hypothesized mechanism for NSI-189 was neurogenesis mainly in the hippocampus .

At day 28, NSI-189 showed a non-significant growth in the hippocampus and amygdala when compared to placebo .

Post-study, the left side of the hippocampus showed a moderate increase (but not statistically significant). There were similar effects on the right side of the amygdala .
buzai232 Aug 31 '19, 09:39AM
NSI-189 is a benzylphiperizine-aminiopyridine, nootropic and neurogenic research chemical created by Neuralstem, Inc. that was derived from pyrazine and nicotinamide. Studies have shown that it stimulates neurogenesis of human hippocampus-derived neural stem cells in vivo and vitro . In healthy adult mice, NSI-189 has been shown to increase the hippocampal volume by 20% and reverse behavioral symptoms in mouse depression models, meaning at the source it could address depression . The hippocampus is responsible for spatial navigation, along with the consolidation of information from short-term memory to long-term memory.NSI-189 base powder

The chemical entity stimulates new neuron growth in the hippocampus, which is an area of the brain that is believed to be contributory in conditions such as post-traumatic stress disorder (PTSD), Alzheimer's disease, and major depressive disorder (MDD).

NSI-189's Method of Action:
Although it has been demonstrated in rats and chimps, the suggestion that having too small of a hippocampus causes depression and other diseases in humans is still technically just a theory. NSI-189 increases hippocampal volume in adult mice by 20%, a region of the brain that is one of the first to suffer damage resulting in memory loss, disorientation, encephalitis, and hypoxia from disease's such as Alzheimer's .

Nsi-189 Effect

1) Enhance cognition and memory formation.
2) Anxiolytic properties.
3) Anti-depressive effect .
4) Treatment of Alzheimer's and Parkinson's disease.
5) Increase coordination.
6) Improves mood.
7) Help fight fatigue.
8) Prevent oxidation within the brain.
9) Treat alcohol related brain damage.
buzai232 Aug 31 '19, 09:30AM
Dihydrotestosterone Stanolone DHT Powder


Stanolone powder
Synonyms: Androstanolone,dihydrotestosterone
Chemical Name: 5A-androstan-17ß -ol-3-one
CAS: 521-18-6
EINECS: 208-307-3
Assay: 98% min.
Molecular Formula:C19H30O2
Mp 178-183℃,
Packing: foil bag or tin.
Character: White crystalline powder.
Melting Point: 176-181 centigrade, Refractive index 27°.
Specification: Enterprise Standard
Usage: For the treatment of male hypogonadism and sperm reducing infertility

The main androgen which is secreted by the testes is of course testosterone. However, in most of the body, the androgenic sign is not carried through by testosterone. In these tissues inluding brain (CNS), skin, genitals - practically everything but muscle - the active androgen is actually dihydrotestosterone (DHT).
buzai232 Aug 31 '19, 09:23AM
It is a great way to further improve our products and repair. Our mission is always to create innovative products to prospects with a superior expertise for Cranberry Extract , Alpha Arbutin , Lespedeza Cuneata Extract , Standing still today and searching into the long run, we sincerely welcome shoppers all around the globe to cooperate with us.
Professional Design Linoleic Acid - Flmodafinil (Bisfluoromodafinil), n-deshydroxyl Fladrafinil, CRL-40,940 – Tong Rui Bio Detail: Nandrolone propionate powder

Flmodafinil (CRL-40,940 ) is a molecule similar to adrafinil and has shown that it is more effective than these two molecules in their indications with fewer side effects. It is a wakefulness-promoting agent used for treatment of disorders such as narcolepsy, shift work sleep disorder, and excessive daytime sleepiness associated with obstructive sleep apnea. Finally, it will be to positively modulate Glutamate receptors as well which is theorized to be the main mechanism of action behind the cognitive benefits of this smart drug. It also works by preventing the breakdown of Dopamine, which helps to improve mood and reduce stress. It is further thought to stimulate the release of Serotonin which can help to regulate sleep as well as lessen anxiety.

Product name : Flmodafinil (Bisfluoromodafinil), n-deshydroxyl Fladrafinil, CRL-40,940
Chemical name : (2-Amino-2-oxoethyl)[bis(4-fluorophenyl)methyl]sulfoniumolate
2-[[bis(4-fluorophenyl)methyl]sulfinyl]-Acetamide
CAS Number : 90280-13-0
Appearance: white crystalline powder
Purity : 99%
MF:C15H13F2NO2S
MW:309.331
Packing: in 25kgs fiber drums
Storage:Keep container unopened in cool, dry place,Keep away from strong light
Shelf Life:24 months from date of production
CRL-40 940 is a kind of awakening accelerator is used for treatment of seizures narcolepsy and shift work sleep disorders and obstructive sleep apnea related disorders such as excessive daytime sleepiness. Modafinil is also widely used in indications abroad, as a cognitive enhancer. Although the mechanism of action of modafinil is not clear, but this material seems to be a selective, relatively weak, atypical dopamine reuptake inhibitor. However, this may not be the only mechanism of action.
buzai232 Aug 31 '19, 09:09AM
What is Centrophenoxine

Centrophenoxine is a member of the family of cholinergic nootropics. Produced synthetically, the compound is a precursor to DMAE (dimethylaminoethanol), which has been proven to improve cognitive function in seniors, especially those diagnosed with a degenerative brain disease like Alzheimer’s. [1]In a separate study, Centrophenoxine also helped improve brain stimulation and the formation of new long-term memories in the elderly population.However, its positive nootropic effects aren’t limited to seniors.
Younger users with healthy brains can also benefit from the enhanced cognitive functions and memory improvement.In addition to the cognitive benefits, Centrophenoxine is thought to have powerful anti-aging properties and has been shown to increase the lifespan in mice by 30-50% in a 2002 study. [2]The supplement can be purchased legally online or in stores at retailers throughout the US in either a powder or a pill form.Older adults with any sort of memory issues, including Alzheimer’s or dementia, as well as younger adults looking to improve their ability to form memories and learn new things can benefit from taking Centrophenoxine.

Centrophenoxine is a very popular supplement within the nootropics community, and based on the research there’s a good reason for it.It delivers similar cognitive enhancement properties to what you’ll see in Alpha GCP but stands apart with the research on the anti-aging and possible longevity-boosting properties. I’m very interested in additional studies and information as it becomes available.Another exciting observation of several online Centrophenoxine users is its ability to produce somewhat instant effects after a one-time use.
While other nootropics may offer similar effects over time, some users theorize that Centrophenoxine can produce lasting memory enhancement benefits after a single cycle of taking the product.
As centrophenoxine is a prodrug from DMAE, it enables the body to remove harmful molecules in the brain that would result in decreased cognitive function.Through its ability to suppress these molecules, centrophenoxine can not only slow down the mental sides of aging, but it can also work to actively reverse them.www.aasraw.com/products/nandrolone-phenylpropionate-powder
buzai232 Aug 31 '19, 09:02AM
Coluracetam is a nootropic supplement

NPP powder is a nootropic supplement that is marketed as being able to enhance mental functioning. Nootropics are a class of supplements that have positive effects on the brain, such as relieving anxiety, enhancing cognitive abilities and boosting motivation.
Coluracetam (also known as MKC-231) is, as stated earlier, a nootropic supplement that is designed to boost mental function. It is in the class of nootropics called racetams, which all have similar effects on the brain and all share similar chemical structures.
1. Enhance mental intelligence.
2. Boost memory and leaning capabilities.
3. Improve brain power to solve problems and protect it from any chemical or physical injury.
4. Enhance motivation level.
5. Enhance the control of cortical/subcortical brain mechanism.
Specification: 98%
Appearance: White Off-white Crystalline Powder
CAS Number: 135463-81-9
Chemical Formula: C19H23N3O3
MOQ: 0.1KG
Normal Package: 1kg/Aluminum foil bag,25kg/Fiber drum
Normal Payment: T/T, L/C, Paypal, Western Union
Lead Time: 3~5 Days
buzai232 Aug 31 '19, 08:55AM
Strawberry is a widely grown hybrid species of the genus Fragaria . It is cultivated worldwide for its fruit. The fruit is widely appreciated for its characteristic aroma, bright red color, juicy texture, and sweetness. It is consumed in large quantities, either fresh or in such prepared foods as preserves, fruit juice, pies, ice creams, milkshakes, and chocolates. Artificial strawberry aroma is also widely used in many industrial food products.Bromantane powder
Strawberries contains approximately 33 kilocalories, is an excellent source of vitamin C, a good source of manganese, and provides several other vitamins and dietary minerals in lesser amounts.
Strawberries contain a modest amount of essential unsaturated fatty acids in the achene (seed) oil.

Product Name:Strawberry Fruit Juice powder
Latin Name:Fragaria Ananassa Duchesne
Appearance: Light red Powder
Particle Size: 100% pass 80 mesh
Active Ingredients: polysaccharides
GMO Status:GMO Free
Packing: in 25kgs fiber drums
Storage:Keep container unopened in cool, dry place,Keep away from strong light
Shelf Life:24 months from date of production

Function:
As strawberry flavor and fragrance Organic freeze dried Strawberry fruit bulk juice powder are among the most popular hedonic characteristics for consumers, they are used widely as desired features in a variety of manufacturing, including foods, beverages, confections, perfumes and cosmetics.Clear heat antipyretic, thirst quenching, diuresis antidiarrheal, pharynx cough.
buzai232 Aug 31 '19, 08:47AM
Anyone with a passing knowledge of biology knows that testosterone is the male growth hormone. It kicks in during puberty and is what makes blokes taller, stronger, hairier and generally moodier than they otherwise would be without it.

In men, testosterone levels generally remain fairly high until around the age of 30 when they start to lower (women also have testosterone, but in smaller amounts). It is responsible for fertility, bone density, sex drive, muscle strength and development, fat storage, and the production of red blood cells.

But testosterone’s applications don’t stop there. In the word of men’s fitness, testosterone boosters in the form of tablets, supplements or injections, can help signal our bodies to build muscle mass. Which sounds ideal if you’re tired of wolfing down turkey steak and chicken breasts in an attempt to add some size to your frame.

Testosterone is associated with increased energy, fat loss, muscle gain, and improved mental function,” says nutritionist and functional medicine practitioner Steve Grant. “And who doesn’t want more energy, better body composition, increased strength and recovery and better cognitive performance?”

So if testosterone is such a wonder-drug, it makes sense that the more we can get in our systems, the better. Not so. While there have been countless scientific studies proving the benefits of testosterone, many of the wider effects are still up for debate. What’s more, the testosterone market is absolutely brimming with misinformation, from self-accredited experts documenting their bulking journeys on YouTube to websites selling an alarmingly broad range of unapproved products.
Scientific studies have for the most part been inconclusive on certain key questions around testosterone supplements. For instance, does upping testosterone provide you with this plethora of health benefits, or does being healthy simply promote increased levels of testosterone? A study published in the medical journal JAMA Psychiatry, for example, noted that men with depression also have low testosterone levels, but could not definitively say whether low testosterone levels cause depression, or depression causes low testosterone levels.

There are also various conflicting studies regarding testosterone and competitiveness among males. Typically, it’s believed that the more testosterone pumping through your veins, the more of an alpha male you are. Thankfully, Swiss researchers put paid to such outmoded thinking in a study that found that men with increased testosterone levels acted more fairly in negotiations than those with lower levels.
Not only that, but abusing testosterone supplements may even have fatal side-effects. A study in the Journal of the American Medical Association found that boosting testosterone levels may lead to an increased risk of heart attack. Meanwhile, there are growing concerns that an over-reliance on testosterone can even induce strokes. So, what’s in it for you?read more
buzai232 Aug 31 '19, 08:25AM
Top Quality API Aniracetam Powder for Nootropic Supplyment CAS



Raw Cardarine powder is anampakine nootropic of the racetam chemical class purported to be considerably more potent than piracetam. It is lipid-soluble and has possible cognition-enhancing effects. It has been tested in animals extensively, Alzheimer's patients, and temporarily impaired healthy subjects.

Applications:
Aniracetam are related to improved mental performance. This includes an increase in memory and possibly even enhanced learning capacity. This may actually occur differently in each person; Some will see strong effects and begin remembering everything while others may just simply beginremembering small and subtle details.
Aniracetam is also considered be very helpful as a focusing agent. Many users note that their attention.Span is increased as well as being able to focus and concentrate much more easily. This also serves to improve mental fluidity, making even simple, routine tasks such as reading and writing (and holding conversations) seem to flow much more easily, without expending as much effort as before using aniracetam Supplements.
buzai232 Aug 31 '19, 08:17AM
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